Musculoskeletal cancer begins in the bones, cartilage, or soft tissues that support the body—sarcomas of the limb, pelvis, or spine. At PSRI Hospital, the orthopaedic oncology unit works alongside musculoskeletal oncosurgeons and medical oncologists to confirm the diagnosis with a biopsy, stage the disease on our multislice CT and MRI, and plan treatment that starts within days, not weeks. The aim is a limb-sparing surgery wherever the tumour pattern allows it.

Every case is reviewed by a tumour board that includes the surgeon, the pathologist who read the biopsy, and the radiation oncologist before a single recommendation is made. The Versius Robotic System supports precise, minimally invasive resections in select bone tumours. Patients come to us from across the NCR and beyond—and many look specifically for Gynecologic Cancer in Delhi expertise when rare uterine sarcomas co-present—because the hospital runs a NABL-accredited lab 24×7 and does not outsource critical pathology.

Our Treatments


A swelling that does not settle, a dull ache that wakes you at night, or a fracture from a minor knock—musculoskeletal tumours often give quiet signs. PSRI Hospital begins with a pain-guided biopsy, mapped beforehand on MRI and multislice CT, so the sample is taken from the most active part of the lesion. The pathology report runs through our NABL-accredited lab, and the tumour board then charts every option: limb salvage surgery, wide excision with reconstruction, or adjuvant therapy sequenced around the operation.

Our orthopaedic oncology team works with the blood bank, the 24x7 dialysis unit, and the dedicated surgical ICU so a complex resection is supported at every stage. If the tumour type responds to systemic therapy, as Ewing sarcoma often does, chemotherapy is given before surgery to shrink the mass. Radiation oncology steps in for margins that need it. For families managing a related diagnosis, our Blood Cancer in Delhi programme runs on the same shared infrastructure.

  • Limb salvage surgery
  • Wide local excision
  • Megaprosthesis reconstruction
  • Bone graft and allograft
  • Rotationplasty
  • Amputation
  • Neoadjuvant chemotherapy
  • Adjuvant chemotherapy
  • Image-guided biopsy
  • Radical resection with soft tissue coverage
  • Pathologic fracture fixation
  • Radiation therapy for sarcoma
  • Metastasis-directed surgery
  • Palliative orthopaedic stabilisation
  • 🇮🇳 India
  • Other Countries


PSRI Hospital

Center Of Excellence

New Delhi

Press Enclave Marg, J Pocket, Phase II,
Sheikh Sarai, New Delhi, Delhi 110017

Key Musculoskeletal Cancer Procedures


Most patients with a primary bone sarcoma are candidates for limb preservation—but getting there depends on how the tumour is mapped, biopsied, and removed. The sequence matters. A poorly placed biopsy can jeopardise a limb-sparing approach entirely, so PSRI Hospital makes the imaging-guided biopsy the first deliberate step. What follows is a reconstruction plan drawn up before the first incision, not improvised in theatre.

Image-Guided Core Biopsy

Limb Salvage Surgery

Megaprosthesis Reconstruction

Wide Excision and Soft Tissue Coverage

Neoadjuvant Chemotherapy

Adjuvant Radiation Therapy

Rotationplasty

Pathologic Fracture Fixation

Metastasis-Directed Resection

Palliative Stabilisation Surgery

Tumour Board Staging Review

Prosthesis Revision Surgery

Conditions That Lead to Musculoskeletal Cancer Care


The list below is what our orthopaedic oncology team sees most often—primary bone sarcomas that start in the skeleton, and soft tissue sarcomas that invade or wrap around it. A persistent, non-mechanical pain that does not ease with rest is the common thread, often dismissed as a sports strain for weeks before imaging. For cancers that spread across systems, such as Gastrointestinal Cancer in Delhi with bony secondaries, the same surgical principles apply.

Osteosarcoma

Ewing Sarcoma

Chondrosarcoma

Synovial Sarcoma

Undifferentiated Pleomorphic Sarcoma

Liposarcoma of the Extremity

Cordoma

Giant Cell Tumour (Aggressive)

Metastatic Bone Disease

When to See an Orthopaedic Oncosurgeon?


Musculoskeletal tumours often start with symptoms that are easy to write off. The pattern that warrants an orthopaedic oncology consult is a pain that persists for more than two weeks without a clear injury, especially if it wakes you from sleep or is unrelated to movement.

When to See an Orthopaedic Oncosurgeon?

Bone pain that wakes you at night

When to See an Orthopaedic Oncosurgeon?

A firm, growing lump on an arm or leg

When to See an Orthopaedic Oncosurgeon?

Unexplained weight loss with deep ache

When to See an Orthopaedic Oncosurgeon?

A fracture from a minor fall or bump

When to See an Orthopaedic Oncosurgeon?

Swelling that does not settle with ice or rest

When to See an Orthopaedic Oncosurgeon?

Limited range of motion in one joint only

When to See an Orthopaedic Oncosurgeon?

Pain that does not respond to physiotherapy

When to See an Orthopaedic Oncosurgeon?

Visible deformity over a bone

When to See an Orthopaedic Oncosurgeon?

Numbness or tingling near a deep mass

When to See an Orthopaedic Oncosurgeon?

Pain that worsens week on week

When to See an Orthopaedic Oncosurgeon?

A hot, tender area over a limb bone

When to See an Orthopaedic Oncosurgeon?

Return of pain after a known cancer elsewhere

Many of these signs overlap with benign conditions, and that is exactly why an early MRI and a specialist review matter. If you have noticed a symptom above, book a consultation for Musculoskeletal Cancer in Delhi at PSRI Hospital, where the biopsy and the treatment plan are sequenced by a tumour board from day one.

Our Team of Experts


Our musculoskeletal oncology team brings together orthopaedic oncosurgeons, medical oncologists, radiation oncologists, and a dedicated sarcoma pathologist. A tumour board meets for every new biopsy result, staging the disease jointly before the surgeon, the chemotherapist, and the radiation team set a sequence. A patient walks out of one discussion with a written plan that covers surgical dates, neoadjuvant cycles, and the prosthetic fitment timeline.

Why PSRI?


PSRI Hospital was established in the year 1996 as South East Asia’s first and India’s foremost institute providing advanced and comprehensive medical and surgical treatment for digestion-related diseases. Since its inception, many more specialties have been added and presently it is a multi-specialty Hospital.

PSRI Hospital is backed by the JK Group one of the leading business houses in India, PSRI was established to provide curative and preventive medical care through a caring environment.

Our team of highly skilled and experienced doctors in Delhi is committed to delivering the highest level of care by using cutting-edge technology & state of art infrastructure to get the best possible results for our patients.

From diagnosis to treatment, we deliver a wide range of services to address all type of diseases. Our team of expert works together to provide a customized and complete care plan for each patient.

Being the best multispecialty Hospital, our primary focus is to provide patient well-being. Therefore, our doctors takes the time to hear patients concerns, answer their questions and offer expert knowledge and support throughout their journey.

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Our Infrastructure & Technology


  • Versius Robotic System
  • Modular Intra Connected OT’s
  • Multislide CT Scan
  • 1.5 TESLA MRI
Our Infrastructure & Technology

Knowledge Center

Stay updated with the latest advancements in healthcare, gain valuable insights from our experts, and discover tips for maintaining a healthy lifestyle. Let us be your trusted source of knowledge on all things related to well-being.

Frequently asked questions (FAQ’s)


Musculoskeletal cancer is a sarcoma that starts in bone, cartilage, or the soft tissues around them. Diagnosis at PSRI Hospital begins with an MRI and a multislice CT to map the lesion, followed by an image-guided core biopsy that is read in our NABL-accredited lab. The report goes straight to the tumour board so the staging is confirmed within days.

Most patients diagnosed early are candidates for limb salvage. The tumour is removed with a wide margin of healthy tissue, and the bone is reconstructed with a megaprosthesis or a bone graft. Whether the limb can be kept depends on the tumour’s response to chemotherapy and its exact relationship to the neurovascular bundle on MRI.

The cost is driven by the implant (a custom megaprosthesis adds significant expense), the number of chemotherapy cycles, the length of ICU stay, and the need for adjuvant radiation. Across Delhi, treatment typically ranges from ₹3 lakh to ₹45 lakh depending on stage and reconstruction type. PSRI Hospital provides a written, line-item estimate after the tumour board review.

Hospital stay after limb salvage surgery is usually 7 to 14 days. Weight-bearing on a reconstructed limb begins under physiotherapy supervision around six to eight weeks post-surgery, and most patients return to independent walking within three to four months. Chemotherapy cycles continue alongside the recovery programme.

PSRI Hospital runs a NABH-accredited oncology programme where the orthopaedic oncosurgeon, medical oncologist, and sarcoma pathologist review every case together. The Versius Robotic System supports precise resections, and the 24x7 blood bank and surgical ICU sit on the same floor. It is recognised as the best cancer hospital in delhi for integrated care.

For Ewing sarcoma and high-grade osteosarcoma, neoadjuvant chemotherapy is given first to shrink the tumour and treat micrometastases early. Surgery follows, and adjuvant chemotherapy continues afterwards. The medical oncology team sequences the cycles around the surgical date so the immune system recovers before the incision.

An MRI of the whole bone and a CT of the chest are done first. The MRI shows the tumour’s extent and its relation to vessels; the CT checks for lung metastases. In Delhi, these two scans together cost roughly ₹20,000 to ₹50,000 across most diagnostic centres. The biopsy is planned from the MRI, never before it.

Yes, and it is standard practice. Sarcomas are rare, and a pathology second read can change the grade. Bring the original biopsy slides and the MRI disc. Our sarcoma pathologist reviews them alongside the oncosurgeon, and the tumour board then produces a written second-opinion report. Phone +91 84 84 84 84 17 to book it.
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