Covishield Side Effects: What is TTS Syndrome, Symptoms, and Danger Signs

The Covid-19 pandemic was the most challenging period for everyone which completely disrupted our daily lives, economies, and healthcare systems. During its peak, vaccination was the best option for survival and recovery. Vaccines like Covishield have played an important role in helping us survive. But, some individuals who received the Covishield vaccine are experiencing some side effects, including a rare but serious condition known as TTS syndrome. In this blog, we will explore what TTS syndrome is, its symptoms, danger signs, and the treatment procedures available. Also, we will learn how a Delhi multispeciality hospital like PSRI provides exceptional care and treatment for such conditions.

Understanding TTS Syndrome

TTS (Thrombosis with Thrombocytopenia Syndrome) is a rare condition characterized by blood clot formation combined with low platelet counts. This syndrome has been observed in some individuals who have received the Covishield vaccine, although it remains extremely rare. It is important to understand TTS because early recognition and treatment can prevent severe complications.

Causes of TTS Syndrome

TTS syndrome involves two main components: thrombosis and thrombocytopenia. Thrombosis refers to the formation of blood clots in the blood vessels, which can obstruct blood flow and lead to serious health issues. Thrombocytopenia, on the other hand, is a condition where the platelet count in the blood is abnormally low. Platelets are essential for blood clotting, and their deficiency can lead to bleeding problems.

The exact cause of TTS after receiving the Covishield vaccine is still being studied. It is believed to be an immune-mediated reaction where the body’s immune system mistakenly attacks its platelets, leading to clot formation. This condition is similar to a reaction seen in some patients treated with heparin, known as heparin-induced thrombocytopenia (HIT).

Symptoms of TTS Syndrome

Recognizing the symptoms of TTS syndrome early is important for timely medical intervention. Symptoms typically appear within 4 to 28 days after vaccination. Here are the common symptoms to watch out for:

• Severe Headache: A persistent and severe headache that does not improve with usual painkillers.
• Visual Changes: Blurred vision, double vision, or sudden vision loss.
• Shortness of Breath: Difficulty in breathing or a feeling of tightness in the chest.
• Abdominal Pain: Severe and persistent abdominal pain.
• Leg Swelling: Swelling, redness, or pain in the legs, which may indicate a blood clot.
• Unusual Bleeding or Bruising: Easy bruising or unusual bleeding, such as nosebleeds, gum bleeding, or blood in urine or stools.

Danger Signs: When to Consult a Doctor

If you or someone you know experiencing any of the following danger signs after receiving the Covishield vaccine, it is important to seek immediate medical attention:

• Persistent and Severe Headache: Especially if accompanied by blurred vision or difficulty in movement.
• Severe Abdominal Pain: That does not go away or gets worse over time.
• Difficulty Breathing: Shortness of breath, chest pain, or a sudden drop in oxygen levels.
• Leg Pain or Swelling: Especially if one leg appears more swollen or painful than the other.
• Neurological Symptoms: Such as seizures, confusion, or loss of consciousness.
• Unusual Bleeding: Any signs of unexplained or severe bleeding.

These symptoms could indicate serious complications, and prompt medical evaluation is essential.

Treatment Procedures and Care

Treatment for TTS syndrome involves addressing both the thrombosis (clotting) and thrombocytopenia (low platelet count). Here are the common steps involved in managing this condition:

Immediate Medical Evaluation: If TTS is suspected, immediate hospitalization and a thorough medical evaluation are required.

Blood Tests: To confirm low platelet count and identify clot formation.

Imaging Studies: Such as ultrasound, CT scan, or MRI to locate blood clots.

Anticoagulation Therapy: Medications to prevent further clotting. However, heparin is avoided due to its potential to worsen the condition. Alternatives like direct oral anticoagulants (DOACs) are used.

Intravenous Immunoglobulin (IVIG): To reduce the immune response causing platelet destruction.

Platelet Transfusion: In severe cases, platelet transfusions might be necessary to manage bleeding complications.

Aftercare: Aftercare involves regular monitoring of platelet counts and clotting parameters, as well as follow-up visits to ensure the condition is under control.

Trust PSRI Hospital for the Best Care

While TTS syndrome is a rare side effect of the Covishield vaccine, understanding its symptoms and getting timely medical care can prevent severe outcomes. PSRI Hospital, a super speciality hospital in Delhi, offers comprehensive and advanced treatment options for managing TTS and other vaccine-related complications. Our experienced team of doctors provides personalized care to ensure the best outcomes for our patients. If you experience any symptoms or have concerns about TTS syndrome after receiving the Covishield vaccine, do not hesitate to contact PSRI Hospital. Our commitment to excellence and patient-centric approach makes us the best hospital in Delhi for managing complex medical conditions. Visit our website or call us to schedule an appointment and ensure you receive the highest quality of care.

FAQs

What is TTS syndrome?

Ans. TTS (Thrombosis with Thrombocytopenia Syndrome) is a rare condition involving blood clots and low platelet counts, sometimes observed after receiving the Covishield vaccine.

What are the symptoms of TTS syndrome?TTS syndrome

Ans. Symptoms include severe headaches, visual changes, shortness of breath, abdominal pain, leg swelling, and unusual bleeding or bruising.

When should I consult a doctor after receiving the Covishield vaccine?

Ans. Consult a doctor if you experience persistent severe headache, severe abdominal pain, difficulty breathing, leg pain or swelling, neurological symptoms, or unusual bleeding.

How is TTS syndrome treated?

Ans. Treatment includes hospitalization, blood tests, imaging studies, anticoagulation therapy (excluding heparin), intravenous immunoglobulin (IVIG), and possibly platelet transfusions.